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Natrapharm
Regulatory Class: Rx
C: Azithromycin monohydrate
I: Treatment of resp tract infections including otitis media; uncomplicated genital, skin & soft tissue infections. Prophylaxis & as a component in the treatment regimen of Mycobacterium avium complex (MAC).
D: Adult 500 mg as a single daily dose for 3 days or initially 500 mg followed by 250 mg daily for a further 4 days. Chancroid & uncomplicated genital infections caused byChlamydia trachomatis 1 g as a single dose. Uncomplicated gonorrhea 2 g as a single dose. Granuloma inguinale Initially 1 g followed by 500 mg daily or 1 g once wkly for at least 3 wk. Prophylaxis of disseminated MAC infections 1.2 g once wkly. Mild or moderate typhoid caused by multidrug-resistant strains 500 mg once daily for 7 days.
A: May be taken w/ meals to reduce GI discomfort.
CI: Severe hepatic impairment. Concomitant use w/ pimozide.
SP: Hepatic or renal impairment.
AR: GI disturbances.
INT: Al- or Mg-containing antacids; lovastatin or other HMG-CoA reductase inhibitors; quinine; nelfinavir; cyclosporin, digoxin, ergot alkaloids, phenytoin; pimozide.
May be taken w/ meals to reduce GI discomfort.